Title:

Metin and Metactomyosin

Creator:

Kaminer, B.
Szent-Gyorgyi, Albert, 1893-1986

Date:

15 December 1963

Description:

This study sought to explain the apparent role of calcium ions in muscle contraction, by searching for a component of muscle tissue that would have an affinity for Ca ions. Reasoning that such material would probably have a structure that included negative groups such as sulfites, and knowing that such molecules were often "metachromatic" (i.e., would stain to a different color than that of the dye applied to them), Szent-Gyorgyi tested various muscle components--myosin, actomyosin, and other fractions--for their ability to turn toluidine blue (a lab stain) purple. He extracted a metachromatic protein and called it "metin."

Periodical:

Proceedings of the National Academy of Sciences of the United States of America

Publisher:

National Academy of Sciences (U.S.)

Rights:

Reprinted with permission from the National Foundation for Cancer Research. For additional copies or more information, please call 1-800-321-CURE or visit our Web site at and http://www.nfcr.org/

Genre:

Articles

Subject:

Muscle Contraction and Calcium

Format:

Text

Extent:

4 pages

Language:

English

Legacy Source Citation:

Periodical. Szent-Gyorgyi, Albert, and B. Kaminer. "Metin and Metactomyosin." Proceedings of the National Academy of Sciences of the United States of America 50, 6 (15 December 1963): 1033-1036. Article. 4 Images.. Proceedings of the National Academy of Sciences of the United States of America

Legacy ID:

WGBBHZ

NLM ID:

101584924X124

Profiles Collection:

The Albert Szent-Gyorgyi Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584924X124

Story Section:

The Institute for Muscle Research, 1947-1972